Wan-Dong Yu

Integrated Single-Cell and Bulk RNA Sequencing Reveals Inflammatory Microenvironment and Glycolysis-Driven Epithelial Proliferation in Benign Prostatic Hyperplasia

Background Benign prostatic hyperplasia (BPH) is a prevalent condition and a leading cause of urinary dysfunction in middle-aged and elderly men. The hyperplasia of prostate stromal and epithelial cells enlarges the prostate, compressing the bladder outlet and resulting in obstructive symptoms. However, the crosstalk b...