Open access
Sep 2026
Engineered CAR-T extracellular vesicles loaded with miR-17-5p inhibitor suppress hepatocellular carcinoma progression
It is demonstrated that NKG2D-targeted third-generation CAR-T EVs exert combined anti-HCC activities through direct tumor cytotoxicity and restoration of NK cell function, providing a novel immunotherapeutic strategy for HCC.
Zhi-Feng Zhou, Hui-Ling Wu, Shen Zhao et al.
· Frontiers in Immunology · 0 citations