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This work presents SaltyMeta, a curated benchmark and web-accessible screening framework for salty or saltiness-enhancing short peptides, and provides benchmark, models, scripts, GitHub, and Streamlit for reproducible screening of food-derived peptides.
This study critically examine recent advances in the functional enhancement of biosynthetically produced proteins and highlights emerging strategies that integrate computational design, artificial intelligence-guided protein engineering, and genetic code expansion to enable precise molecular-level customization.
Integrative transcriptomic and proteomic analyses revealed that SRP reversed the downregulation of core genes and key proteins, modulating multiple vascular homeostasis pathways including calcium signaling, vascular smooth muscle contraction, Toll-like receptor signaling, and neuroactive ligand-receptor interaction.
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