Construction of gelatin-based rutin delivery systems by ultrasound/pH-shifting pretreatment and polysaccharide modulation.
This study investigated the effects of polysaccharide types (chitosan oligosaccharide (COS), dextran, and soybean soluble polysaccharide (SSPS)) and ultrasound intensity (0, 300, and 500 W) on rutin-loaded gelatin nanoparticles prepared by pH-shifting. Ultrasound-assisted pH-shifting modified gelatin conformation, prom...