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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

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Wanxia Zhao

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Aug 2026

Mechanistic Decoupling of the cis - and trans -Cleavage Activities of Cas12a via Phosphorothioate-Induced Kinetic Trapping

It is demonstrated that the availability of the RuvC catalytic channel is determined not by induced fit binding but by the chemical cleavability of the occupant, which provides a theoretical framework and additional insights for developing more precise gene-editing tools and designing Cas12a-based in vitro diagnostic p...

Chenqi Niu, Yiyi Mi, Wanxia Zhao et al. · 0 citations

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