Warren M. Casey

ToxCompl Completion of the DrugMatrix Toxicogenomics Database: An Integrated Resource for Toxicological Hypothesis Generation.

The DrugMatrix database contains systematically generated toxicogenomics data from short-term in vivo studies for over 600 chemicals. However, most potential endpoints are missing due to a lack of experimental measurements. Therefore, we leveraged matrix factorization and machine learning methods to predict the missing...