Open access
Aug 2026
Evaluation of population-specific polygenic risk scores for blood lipids: insights from Taiwanese cohorts and multiancestry meta-analysis
Background Blood lipids are heritable risk factors for cardiovascular disease (CVD), a leading cause of mortality worldwide. However, the genetic architecture of lipid traits and the performance of polygenic risk scores (PRSs) remain underexplored in East Asian (EAS) populations, including Taiwanese Han individuals. Me...
Yu-Chia Chen, Ting-Yuan Liu, Chi-Chou Liao et al.
· Frontiers in Bioinformatics · 0 citations