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Open access Sep 2026

Dynamic PD-L1 Imaging with a NIR-II Fluorescent Probe for Monitoring and Precision Radio-Immunotherapy in Triple-Negative Breast Cancer

Programmed death-ligand 1 (PD-L1) is a dynamic biomarker relevant to radiotherapy and immunotherapy, motivating the development of noninvasive approaches for longitudinal assessment. Here we report a PD-L1–targeted near-infrared II (NIR-II) fluorescent probe, PNF-ICG, generated by conjugating a cyclic PD-L1–binding p...

Zhan-Yuan Li, Kang Zhu, Ying Wu et al. · 0 citations

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