Author

Wei Li

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Open access Aug 2026

Mammalian TMC Family Proteins are Mechanically Gated Ion Channels

Every known life form senses and reacts to mechanical forces. These mechanical stimuli can be converted into electrical signals by mechanically gated ion channels, a transduction cascade pivotal to numerous physiological functions including touch, hearing, mechanical pain, circulation, gastrointestinal function, and me...

Songdi Fu, Jianying Dong, Xing Luo et al. · bioRxiv · 0 citations

Review Open access Aug 2026

Efficacy and safety of intravenous methadone for pain management in cardiac surgery: a systematic review and meta-analysis

Objectives To evaluate the analgesic efficacy and safety of intraoperative intravenous methadone compared with conventional opioid-based analgesic regimens in adult patients undergoing cardiac surgery, using data derived from randomized controlled trials and retrospective cohort studies. Methods A comprehensive retriev...

Wei Li, Yuandi Ye, Jian-Qiong Zhou et al. · Frontiers in Medicine · 0 citations