Wei Liu

In Vivo Chemical Cross-Linking Coupled with Reversed-Phase Co-Fractionation Mass Spectrometry Enables Protein Complex Analysis

Understanding protein–protein interactions (PPIs) and the architecture of protein complexes is essential for elucidating cellular functions and drug action mechanisms. Co-fractionation mass spectrometry (CF-MS) has emerged as an effective tool for analyzing protein complexes under near-native conditions, however, its...