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Review Open access Jul 2026

Brain heart crosstalk after ischemic stroke toward a unified framework for pathophysiology and precision medicine

Background Acute ischemic stroke and cardiac dysfunction engage in a complex bidirectional interplay that critically determines patient outcomes. Despite growing recognition of the brain-heart axis, a comprehensive mechanistic framework integrating traditional and emerging pathways remains lacking. Moreover, existing r...

Pengpeng Li, Yangyang Gao, Wei Liu · 0 citations

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