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Open access Sep 2026

Global trends in gastric cancer burden among adolescents and young adults

Gastric cancer (GC) in adolescents and young adults (AYA; 15–39 years) is rare but clinically distinct. Contemporary global estimates and temporal drivers – particularly age–period–cohort (APC) effects and socioeconomic differentials – remain unclear. We conducted a secondary analysis using data from the Global Burden...

Mao-Qiang Liu, Zhen-Zhen Peng, Wei Liu et al. · 0 citations
Open access Jul 2026

Integrated Single-Strand DNA Capture and Haplotype-Guided Variant Calling Platform for Non-Invasive Prenatal Testing of Monogenic Disorders

Background/Objectives: Non-invasive prenatal testing for monogenic disorders (NIPT-MD) provides a safe alternative to invasive procedures. However, its clinical utility is often limited by challenges such as low fetal fractions (FF), technical artifacts, and the difficulty in resolving maternally inherited pathogenic v...

Jie Shen, Wei Liu, Li Lu et al. · 0 citations

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