Clusterin interference decreases cerebral ischemia/reperfusion injury by suppressing TFR1-dependent ferroptosis.
Ferroptosis plays a crucial role in the pathological process of cerebral ischemia-reperfusion (I/R) injury, but the specific regulatory mechanism of Clusterin in this process remains unclear. This study aims to investigate whether interfering with Clusterin can alleviate cerebral I/R injury by regulating neuronal ferro...