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Review Open access Sep 2026

Pathophysiological Effects and Targeted Therapy Strategies of Neutrophil Extracellular Traps in Ischemia–Reperfusion Injury

Ischemia–reperfusion injury (IRI) is a common form of tissue injury encountered in myocardial infarction, ischemic stroke, solid-organ transplantation, and complex vascular surgery. Timely restoration of blood flow is essential for salvaging ischemic tissues; however, reperfusion itself can induce sterile inflammation...

Yan-Ning Lv, Lin-Wu Kuang, Zhi-Han Xiao et al. · 0 citations
Open access Aug 2026

Integrative single-cell eQTL and GWAS analyses identify cell-type-specific regulatory mechanisms underlying ESCC susceptibility.

Interpreting genetic risk variants within their relevant cellular contexts remains a central challenge in esophageal squamous cell carcinoma (ESCC), a malignancy with a substantial inherited component. We integrate single-cell RNA sequencing with genotype data to generate a cell-type-resolved expression quantitative tr...

Lina Song, Miao-Xin Pan, Yue-Ping Li et al. · 1 citation

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