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Open access Oct 2026

Comprehensive analysis and external validation of a glycolysis-related gene signature as a prognostic index for skin cutaneous melanoma.

Skin cutaneous melanoma (SKCM) is the third most common cause of cancer-related deaths globally. Today, precise biomarkers to predict melanoma prognosis are quite limited. Aerobic glycolysis serves as the primary metabolic pathway for malignancies to meet their rapid growth demands. This study built a glycolysis-associ...

Chen-Shan Jiang, Sen Niu, Chen Li et al. · 0 citations
Open access Sep 2026

Preoperative risk stratification for postoperative inflammatory–nutritional deterioration after colorectal cancer surgery: an interpretable machine learning study

Postoperative inflammatory–nutritional deterioration may adversely affect recovery after colorectal cancer surgery. This study aimed to develop and internally validate an interpretable machine learning model for preoperative prediction of postoperative modified Glasgow Prognostic Score (mGPS) = 2. This singl...

Yin-Chao Zhang, Ying-Kun Hu, Xin-Ke Cao et al. · 0 citations
Open access Jul 2026

Prediction of acute postoperative protein depletion risk in colon cancer using an in-context learning foundation model: a retrospective cohort study

Background Acute postoperative protein depletion, including hypoalbuminaemia and hypoproteinaemia, frequently complicates colon cancer surgery and exacerbates adverse outcomes, yet early risk stratification remains challenging. Aims To develop a predictive model utilising a tabular foundation model for acute postoperat...

Xinke Cao, Linrui Han, Xinquan Zan et al. · 0 citations

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