Author

Wei-Shen Chen

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Open access Oct 2026

A deep learning model for detection and staging of osteonecrosis of the femoral head on x-ray images: a retrospective, large-scale, multicentre study in China.

A deep learning-based diagnostic model for the automatic detection and staging of osteonecrosis of the femoral head using x-ray images is developed and its performance with clinicians is compared to allow them to improve their diagnostic performance.

Zhan-Qi Wei, Shi-Peng Hu, Han-Yang Sun et al. · The Lancet Digital Health · 0 citations

Open access Sep 2026

Multi-Omics Analysis Identifies TTYH3 and MPG as Candidate Osteoporosis-Associated Biomarkers in Osteoblasts and Characterizes Spatial Heterogeneity of SPP1 in the Osteoporotic Bone Microenvironment

Background: Osteoporosis (OP) arises from dysregulated bone metabolism driven by genetic and epigenetic factors. Osteoblasts are central to bone formation, and their functional heterogeneity—shaped by genetic background and receptor expression profiles—may critically influence OP susceptibility. This study aimed to ide...

Heng-Yi Diao, Qian-Ning Li, Yu-Cheng Tu et al. · Biomedicines · 0 citations