Wei-Xi Zhang

NCAPD3 induces M2 polarization of peripheral macrophages in lung adenocarcinoma by promoting the binding of E2F1 to the FOXM1 promoter region.

Serving as a highly prevalent malignant tumor, lung adenocarcinoma (LUAD) is frequently associated with the establishment of an immunosuppressive tumor microenvironment during its initiation and progression, where M2-polarized macrophages exert pivotal effects. NCAPD3 acts as an oncogenic driver in multiple tumors; how...