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Author

Wei Zhang

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Open access Oct 2026

Relationship Between Fall Risk and Risk of Acute Kidney Injury in Patients with Acute Myocardial Infarction: A Multicenter Retrospective Study.

Background Acute kidney injury (AKI) is a frequent complication in patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI), significantly increasing mortality. The Huaxi Fall Risk Assessment (H-FRA) scale, a multidimensional bedside tool, may indirectly reflect AKI risk throu...

Qin Sun, Jing Yu, Ai-Ai Li et al. · 0 citations
Review Aug 2026

Beyond the ATP-binding pocket: emerging strategies in kinase targeting from allosteric inhibition to targeted protein degradation.

The structural and medicinal chemistry principles underlying (i) allosteric inhibition and (ii) proximity-induced degradation are summarized, with an emphasis on design logic, structure-activity relationships, and key liabilities in the beyond rule of five space.

Mei Zhou, Linshan Li, Xiao-Juan Tang et al. · 0 citations

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