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Open access Sep 2026

Global and regional burden, trends, and future projections of laryngeal cancer (1990-2041).

Laryngeal cancer remains a significant global health challenge, with notable disparities across regions, socioeconomic strata, age groups, and genders. Using Global Burden of Disease data (1990-2021), we evaluated prevalence, incidence, mortality, and disability-adjusted life years across 204 countries and 21 regions s...

Jing Liu, Wei Zhu, Yong-Cu Sun et al. · 0 citations
Open access Sep 2026

Histone H3K18 Lactylation Drives Immunosuppression by Upregulating CD38 in Myeloid-Derived Suppressor Cells in Lung Cancer.

Histone lactylation is an epigenetic modification that connects lactate metabolism with protein function. Our study identified lactate enhances the protein lactylation level not only in Myeloid-derived suppressor cells (MDSCs) of tumor-bearing mice, but also in the tumor tissues of lung cancer patients. This modificati...

Yao Dai, Hai-Yan Dai, Ya-Hui Wang et al. · 0 citations

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