R-loop-related prognostic signature in colorectal cancer: data-analysis pipeline
Data-analysis pipeline for a cross-cohort study of an R-loop-related gene-expressionprogramme in colorectal cancer, built entirely on public data. The pipeline constructs a CRC-specific R-loop candidate gene set, fits a penalised Cox model inTCGA-COAD/READ and evaluates the resulting score in five independent GEO cohor...