Review
Open access
Aug 2026
Regulated Cell Death in Calcium Oxalate Stone Disease: From Tubular Epithelial Injury to Inflammatory Amplification
Abstract Calcium oxalate (CaOx) stone disease begins with urinary supersaturation. However, crystallization alone does not explain crystal retention, lesion progression, or inflammatory amplification. Current evidence suggests that crystal-exposed renal epithelium undergoes regulated stress responses that alter adhesio...
Xijie Ding, Chao-Yue Ji, Guojun Chen et al.
· Journal of Inflammation Rese... · 0 citations