Author

Weixiong Jian

2 papers indexed here

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Open access Aug 2026

Single-Cell and Machine Learning Analyses Identify a PFKFB3-Centered Regulatory Network and Potential Salidroside Interaction in Coronary Heart Disease

The findings support PFKFB3 as a potential biomarker and mechanistic hub and suggest that salidroside may modulate its activity and provide a multi-layered framework connecting glycolytic remodeling, inflammatory transcriptional activity, and intercellular signaling in CHD.

Hao-Bo Yang, Yonghui Zhang, Yun-Feng Yu et al. · International Journal of Mol... · 0 citations

Review Open access Aug 2026

The NRF2 signaling pathway in hepatocellular carcinoma: dual roles, epigenetic reprogramming, and therapeutic opportunities in metabolic vulnerability

Hepatocellular carcinoma (HCC) is a highly heterogeneous malignant tumor with a poor prognosis; its onset and progression are closely associated with persistent oxidative stress and metabolic reprogramming. Nuclear factor E2-related factor 2 (NRF2), as a key transcription factor regulating redox homeostasis, exerts a c...

Yue Wang, Lingwei Gao, Hao-Bo Yang et al. · Frontiers in Oncology · 0 citations