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Wen-Bao Qi

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Oct 2026

Structure-based design and immunogenicity of an H5 hemagglutinin stem nanoparticle vaccine candidate.

Highly pathogenic avian influenza viruses (HPAIVs), particularly the H5N6 subtype, pose a serious global public health threat. Conventional influenza vaccines primarily target the highly variable globular head of hemagglutinin (HA), resulting in limited breadth of protection. Here, we employed a structure-guided vaccin...

Ao-Jie Wang, Yi Liu, You-Qin Yin et al. · 0 citations
Open access Aug 2026

Comparative Immunogenicity of Inactivated H7N9 Avian Influenza Vaccines with Different Internal Gene Backbones

The findings suggest that internal gene backbone compatibility may influence vaccine immunogenicity and warrant further validation to support a refined vaccine design strategy for H7N9 and potentially other avian influenza subtypes.

Yi Liu, Meng-Yuan Bai, Tao Zhang et al. · 0 citations

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