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Wen-Bin Yao

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Open access Aug 2026

NKAIN1 predicts poor prognosis and associated with drug resistance and immune infiltration in prostate adenocarcinoma

Na, K-ATPase interaction 1 (NKAIN1) is a transmembrane protein that can interact with Na, K-ATPase β1 subunit. NKAIN1 has prognostic value in several cancers, but its biomarker and carcinogenic roles in the development of prostate adenocarcinoma (PRAD) remain underexplored. The Cancer Genome Atlas (TCGA) d...

Xuan-Cai Chen, Cong Wang, Xingming Qu et al. · 0 citations
Open access Jul 2026

Integrated single-cell and spatial transcriptomics reveals a multicellular program contributing to immunotherapy resistance and adverse clinical outcomes in clear cell renal cell carcinoma.

This study defines a spatially organized, functionally coordinated multicellular niche that drives ICB resistance in ccRCC, establishing both a predictive biomarker for patient stratification and a mechanistic framework for therapeutic intervention.

Wen-Bin Yao, Jia Qi, Xinyi Zheng et al. · 0 citations

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