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Wen-Bo Du

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Open access Aug 2026

Integrative multi-omics identifies a four-gene diagnostic signature linking immune dysfunction and airway remodeling in COPD

Four lung-derived COPD-associated candidate genes were identified and CEP55 and ATP6V0D2 showed the strongest peripheral-blood diagnostic performance and biological plausibility, supporting their prioritization as candidate circulating biomarkers for further validation.

Wen-Bo Du, Yu-Kun Wang, Xiang Li et al. · 0 citations

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