Wen-Bo Gao

Entropy-Engineered Aptamer Truncation Enables Dual-Mode LRET/SERS Aptasensing for Multiplex Detection of Phalloidin and α-Amanitin in Mushroom Samples.

Phalloidin (PHD) and α-amanitin (α-AMT) are structurally constrained cyclic mushroom toxins whose rigid structures and limited accessible recognition surfaces challenge high-affinity molecular recognition and sensitive multiplex detection. Here, we report an entropy-guided aptamer engineering strategy that removes redu...