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Author

Wen-Chi Su

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2 papers indexed here

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Open access Aug 2026

Maraviroc Inhibits SARS-CoV-2 Through Variant-Dependent Effects on Viral Entry and Mpro Activity Using Single-Round Infectious Particle and Virus-like Particle Models

It is demonstrated that MVC exerts variant-dependent antiviral effects by targeting viral entry, modulating trafficking pathways, and inhibiting Mpro activity against SARS-CoV-2 variants, providing insights into its potential therapeutic application.

U. Le, Po-Ju Chen, Li-Wei Chu et al. · 0 citations
Review Open access Jul 2026

Host protein cleavage by Dengue and Zika virus NS3 proteases: from substrate identification to potential biological consequences

Dengue virus (DENV) and Zika virus (ZIKV) are medically important orthoflaviviruses that utilize the multifunctional NS3 protease, in complex with its cofactor NS2B, for viral replication and host modulation. Here, we summarize current knowledge of host proteins targeted by NS3 proteases and discuss recent advances in...

U. Saidu, Bbumba Patrick, Wen-Chi Su · 0 citations

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