Author

Wen-Chong Ye

h-index 8 View on Semantic Scholar

We have 2 of 25 papers

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Sep 2026

Discovery of a Broad-Spectrum Antiviral Compound against Porcine Reproductive and Respiratory Syndrome Virus

Porcine reproductive and respiratory syndrome virus (PRRSV) causes substantial economic losses to the swine industry, while vaccine-based control remains challenges. The study performed structure−activity relationship (SAR)-guided optimization of tylvalosin, yielding 42 novel derivatives. Compound V-28 exhibited the...

Xiao-Pei Yang, Ru-Meng Ma, Ying-Hong Long et al. · Journal of Medicinal Chemist... · 0 citations

Jul 2026

A xanthone derivative MGS-3, confers protection against Staphylococcus aureus infection through SarA-mediated inhibition of alpha-hemolysin expression.

Results establish SarA suppression as MGS-3's primary anti-virulence mechanism, and MGS-3 represents a promising candidate for anti-staphylococcal drug development, targeting virulence rather than bacterial viability to potentially curb resistance evolution.

Han Bai, Yuehan Zhou, Wen-Chong Ye et al. · Microbial Pathogenesis · 0 citations