Author

Wen-Guang Chen

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Review Open access Sep 2026

Knee Osteoarthritis Therapy Targeting NLRP3 Inflammasome: Progress From Mechanism to Application

This paper briefly reviews the structure, function, and activation mechanism of the NLRP3 inflammasome and its molecular role in the pathogenesis of knee osteoarthritis (KOA), and explores the potential value of traditional Chinese medicine (TCM) in treating KOA by modulating NLRP3 inflammasome activity. The review cov...

Wen-Guang Chen, Bao-Xiu Yi, Zhan-Kun Wang et al. · Immunity, Inflammation and D... · 0 citations

Open access Oct 2026

Effect of Sidewall Corner Modification on the Flow Pattern in the Forebay of a Side-Inlet Pumping Station

To mitigate the severe recirculation and sediment deposition induced by highly sediment-laden flow in the lateral-inflow forebay of the No. 3 Pumping Station in Hong sipu, Ningxia, within the Yellow River Basin, this study investigates the effects of different corner configurations of the left and right sidewalls on th...

Sui-Ju Lv, Ying-Ying Gao, Wen-Guang Chen et al. · Water · 0 citations

Open access Sep 2026

Joint Assessment of Triglyceride-Glucose Index and Non-Traditional Lipid Parameters for Incident Stroke Risk in Middle-Aged and Older Chinese Adults: A Prospective Cohort Study Based on CHARLS.

BACKGROUND The triglyceride-glucose (TyG) index and non-traditional lipid parameters have been linked to cardiovascular and cerebrovascular risk, but longitudinal evidence on their combined utility for predicting incident stroke remains limited. We aimed to evaluate the associations between composite indices integratin...

D. Xiao, Liang Zhou, Ying-Feng Xiao et al. · Journal of Stroke & Cerebrov... · 0 citations