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Author

Wen-Hao Zhou

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Open access Aug 2026

Multiplexed Quantification of Variant Abundance in the Globin Gene Family: Integrating Saturation Mutagenesis with Cross-Paralog Prediction

Widespread genetic testing has expanded variant identification, yet functional characterization remains a bottleneck in genome guided medicine. Here, we present a modified Variant Abundance by Massively Parallel Sequencing (VAMP-seq) platform integrating experimental and computational approaches for high-resolution abu...

Xiao-Li Cai, Dao-Yi Wang, Jia-Meng Hu et al. · 0 citations
Open access Sep 2026

Temporal trends, pathogen distribution, and forecasted burden of neonatal meningitis in China (1990–2023): A descriptive analysis based on Global Burden of Disease 2023

Neonatal meningitis remains an important cause of mortality and health loss. We characterized temporal trends, pathogen distributions, and risk‐attributable burden in China using Global Burden of Disease (GBD) 2023 estimates. We analyzed GBD‐modeled incidence, mortality, disability‐adjusted life years, yea...

Meng-Ya Sun, Meng-Meng Ge, Lu-Kun Tang et al. · 0 citations

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