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Author

Wen-Hu Zhou

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Sep 2026

Stepwise neutrophil-to-neuron targeting nanotherapy for mitochondrial protection and blood-brain barrier preservation in ischemic stroke.

Ischemic stroke is a leading cause of mortality and long-term disability worldwide, yet the clinical efficacy of reperfusion therapies remains severely constrained by a narrow therapeutic time window and secondary ischemia-reperfusion injury. Preserving the viability of the ischemic penumbra through early, multi-target...

Xu-Rui Gu, Sai Wang, Lei Chen et al. · 0 citations
Review Open access Aug 2026

Antibacterial Immunotherapy: Mechanistic Insights, Emerging Therapeutic Strategies, and Clinical Translation

This narrative review first examines the biological mechanisms underlying bacterial resistance, then explores therapeutic strategies beyond conventional antibiotics, providing an overview of current approaches and their limitations, including drug repurposing, bacteriophage therapy, and CRISPR-Cas technology.

Hamdi Al-Azzani, Hanane Aliouat, Hongshi Cheng et al. · 0 citations

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