Wen-Hua Zhou

Research progress on the metabolic fate of citrus flavonoids and strategies to improve bioavailability

Citrus flavonoids have various health-promoting effects, such as antioxidant, anti-inflammatory, and metabolic regulatory activities, whereas their low oral bioavailability greatly impairs their in vivo efficacy. Substitution patterns of hydroxyl, methoxyl, and glycosyl groups determine their metabolic fate. As a narra...