Substance use disorder (SUD) is characterized by the persistent prioritization of drug-related cues, which readily trigger intense craving and relapse even after prolonged abstinence. Although previous studies have primarily focused on the mesolimbic dopamine system and fronto-striatal circuits, the mechanisms underlyi...
Man-Qing Wu, Wen-Hua Zhou, Min Zhao· Zhejiang da xue xue bao. Yi...· 0 citations
With recreational cannabis use rising globally, understanding and preventing cannabis use disorders (CUD) has become increasingly important. Cupertino et al.'s recent study (2025) sheds light on the development mechanism of CUD. Our commentary briefly highlights their key findings and the clinical significance of their...
OBJECTIVES
To elucidate the Δ⁹-tetrahydrocannabinol (THC)-like discriminative stimulus effects of 4F-ABUTINACA and to investigate the potential mechanisms underlying anxiety-like behaviors induced by chronic 4F-ABUTINACA administration.
METHODS
A THC drug discrimination procedure was used in adult male rats to evalua...
Bao-Bao Shi, Hai-Tao Wang, Wen-Hua Zhou et al.· Zhejiang da xue xue bao. Yi...· 0 citations
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