Open access
Sep 2026
Crosstalk between exosomes and cellular senescence: A core vicious loop promoting α-synuclein pathology in Parkinson's disease.
ABSTRACT Parkinson's disease is characterized by α-synuclein aggregation, dopaminergic neuron loss, and neuroinflammation. Emerging evidence reveals complex crosstalk between exosomes and cellular senescence in Parkinson's disease pathogenesis. Exosomes mediate α-synuclein transmission and neuroinflammation, while deli...
Wen-Wei Mao, Wen-Hao Song, Yu-Hang Zhang et al.
· Neural Regeneration Research · 0 citations