Open access
Aug 2026
LNP-mediated silencing of oncogenic lncRNA PVT1 enhances chemotherapeutic efficacy in osteosarcoma
Osteosarcoma is an aggressive bone malignancy characterized by early metastasis, chemoresistance, and poor prognosis, particularly in recurrent or metastatic cases. The long non-coding RNA PVT1 has been implicated as an oncogene in various cancers, but its therapeutic potential in osteosarcoma remains underexplored. Th...
Jian-Tong Wei, Ze-Tao Qian, Qing-Qing Qin et al.
· Biochemistry and Biophysics... · 0 citations