Wenjie Chen

Study on the homeostasis mechanism of in vivo degradation of PCL microsphere fillers.

It is demonstrated that PCL microsphere fillers achieve a homeostasis of safety at 12 months through a sequential process involving "surface erosion-cellular involvement-collagen encapsulation" and maintain a homeostasis of efficacy for at least 30 months via a collagen remodeling strategy characterized by "initial rei...