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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Wen-Jie Liu

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Open access Sep 2026

Metformin Inhibits Trophoblast Ferroptosis by Suppressing ATF2 and Activating the PI3K/Akt/Nrf2 Pathway to Improve Gestational Diabetes Mellitus

Gestational diabetes mellitus (GDM) is a common metabolic disorder during pregnancy. Metformin (MET) has emerged as a promising alternative to insulin, but its mechanism of action in the placenta remains incompletely understood. In this study, we aimed to examine whether MET counteracts high‐glucose‐induced ferroptosis...

Dan-Dan Xia, Yu-Hui Zhang, Wen-Jie Liu et al. · 0 citations

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