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Wen-Jie Wang

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Open access Jul 2026

A study on the mechanism of action of B7H4 in HER2-positive gastric cancer and its sensitivity to trastuzumab therapy

Background Human epidermal growth factor receptor 2 (HER2)-positive gastric cancer (GC) is characterized by high malignancy and a poor prognosis. Trastuzumab is the first-line targeted therapy for this disease, but the frequent development of primary and acquired resistance severely compromises treatment efficacy and i...

Qiang-Zu Shao, Fan Zhang, Wen-Jie Wang et al. · 0 citations

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