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Author

Wen-Jing Wei

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Review Aug 2026

Molecular targeting of CDK9 in oncology therapeutics: avenues for translational impact.

The molecular functions of the CDK9/positive transcription elongation factor b (P-TEFb) axis, its role in super-enhancer-driven oncogenic programs, and the mechanisms by which CDK9 inhibition promotes apoptosis, epigenetic derepression, and tumor microenvironment remodeling are summarized.

Ti-Yao Liu, Zhongran Liu, Wen-Jing Wei et al. · 0 citations

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