Review
Aug 2026
Molecular targeting of CDK9 in oncology therapeutics: avenues for translational impact.
The molecular functions of the CDK9/positive transcription elongation factor b (P-TEFb) axis, its role in super-enhancer-driven oncogenic programs, and the mechanisms by which CDK9 inhibition promotes apoptosis, epigenetic derepression, and tumor microenvironment remodeling are summarized.
Ti-Yao Liu, Zhongran Liu, Wen-Jing Wei et al.
· Expert opinion on therapeuti... · 0 citations