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Wen-Jing Zhou

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Oct 2026

Reprogramming tumor-associated macrophages via ID3 mRNA delivery for enhanced immunotherapy in pancreatic cancer.

Pancreatic ductal adenocarcinoma (PDAC) features a profoundly immunosuppressive tumor microenvironment dominated by tumor-associated macrophages (TAMs), which facilitate immune evasion and compromise immunotherapeutic efficacy. The interaction between signal regulatory protein α (SIRPα) on macrophages and cluster of di...

Wen-Jing Zhou, Hao-Yang Wang, Yu-Ting Li et al. · 0 citations

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