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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Wen-Ju Zhang

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Open access Sep 2026

Food derived raffinose attenuates cyclophosphamide-induced immunosuppression in mice with associated changes in gut microbiota, short-chain fatty acids and intestinal barrier integrity.

BACKGROUND Cyclophosphamide (CTX)-induced immunosuppression is accompanied by systemic immune impairment and intestinal dysbiosis. This study evaluated whether raffinose (Raf), a food-derived prebiotic trisaccharide, is associated with improved immune and intestinal outcomes during CTX challenge. RESULTS Forty male I...

Peng Zhang, Tian-Yi Zhang, Qi-Cheng Lu et al. · 0 citations
Open access Sep 2026

Reduced gut microbiota-derived indole-3-carboxaldehyde and 5-hydroxyindole-3-acetic acid are associated with intestinal barrier dysfunction and inflammation in diarrheic suckling lambs

Diarrhea in suckling lambs is associated with gut microbiota dysbiosis, impaired intestinal barrier function, and enhanced inflammatory responses. However, the specific intestinal microbes and microbial metabolites linked to intestinal homeostasis in suckling lambs remain unclear. In this study, diarrheic lambs showed...

Jia-Hao Li, Zheng-Li Wang, Xiao-Xue Ma et al. · 0 citations

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