Author

Wen-Jun Yang

2 papers indexed here

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Jul 2026

Drug-likeness defects drive carrier-free cyanine-PROTAC self-assembly for tumor-specific protein degradation.

A versatile supramolecular strategy that directly addresses the long-standing delivery challenges of PROTACs and advances precise, controllable oncological therapy is established.

Zhenhai Pan, Taian Lin, I. Ullah et al. · Journal of Controlled Releas... · 0 citations

Sep 2026

Proteolysis-Targeting Chimera-Loaded Hydrogel Dressings Orchestrate Immunoregulation and Angiogenesis to Promote Tissue Regeneration in Large Diabetic Wounds.

The delayed healing of diabetic wounds is primarily attributed to a persistent excessive inflammatory microenvironment and impaired angiogenesis. Here, we identify the STimulator of INterferon Genes (STING) as a key regulator driving this pathological state within the wound milieu. To address this, we developed SD-Gel,...

Wen-Jun Yang, Yan-Dong Zhao, Min-Jian Liao et al. · Acta Biomaterialia · 0 citations