Wen-Li Li

Substituent Effects in Amine Enantiodiscrimination Using 19F Molecular Probes and Development of a Predictive Design and Screening Tool

The structural features of 19F molecular probes are critical for effective enantiodiscrimination, with substituent effects, arising from the electronic and steric properties of functional groups, playing a pivotal role in modulating chiral recognition. To systematically investigate these effects, three newly designed...