Accurate detection and quantification of EGFR mutations are essential for molecular stratification in non‐small cell lung cancer (NSCLC). While next‐generation sequencing (NGS) enables comprehensive genomic profiling, droplet digital PCR (ddPCR) offers high sensitivity for predefined mutations. Large‐scale evaluati...
Ming Liu, Lin-Ping Lu, Qifang Lei et al.· iMetaMed· 0 citations
OBJECTIVE
As global smoking rates decline, Lung Cancer in Never-Smokers (LCINS) has emerged as a distinct and increasingly important clinical entity. However, its underlying pathogenesis remains poorly understood, highlighting the need to identify circulating molecular determinants and candidate biomarkers.
METHODS
G...
Jian-Cong Wu, Qi Zhang, Yan-Ming Lin et al.· Current Medicinal Chemistry· 0 citations
BACKGROUND
Myocardial ischemia/reperfusion injury triggers profound metabolic reprogramming and lactate accumulation. However, how this metabolic stress regulates inflammatory gene expression remains poorly understood. We hypothesized that lactylation, a lactate-derived posttranslational modification, links metabolic s...
Su-Yun Chen, Si-Man Shen, Wen-Mei Su et al.· Circulation· 0 citations
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