Wen-Qing Chen

Single-cell and spatial mapping reveals GCLC+ mesenchymal tumor cells linked with favorable outcomes in TNBC

Oxidative stress response (OSR) is suggested as a therapeutic target in triple negative breast cancer (TNBC). However, the cell type specificity and spatial distribution of OSR genes and proteins remain poorly defined. We re-analyzed public datasets, demostrating high OSR gene expression in TNBC tumor cells. We gener...