Author

Wen-Sheng Xie

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Review Open access Sep 2026

Copper homeostasis in macrophages: regulatory mechanisms and immunological implications

Copper is an essential micronutrient whose redox activity underpins a dual role in immunity: it serves as both an antimicrobial effector and a regulator of inflammatory signaling. Macrophages, as central orchestrators of innate and adaptive immunity, maintain sophisticated copper homeostasis mechanisms that dynamically...

Wan-Ting Yang, Jun-Feng Wang, Zhen-Bin Dong et al. · Frontiers in Chemistry · 0 citations

Review Aug 2026

Biomaterial-based microenvironment remodeling for functional regeneration of scarred uterus tissue.

Cesarean section-induced uterine scar defects represent a growing global clinical challenge characterized by fibrosis-dominated healing, mechanical dysfunction, and impaired reproductive outcomes. Current surgical interventions fail to restore the structural and functional integrity of the myometrium, highlighting the...

Wan-Ting Yang, Ying Xu, Wen-Sheng Xie et al. · Journal of materials chemist... · 0 citations

Jul 2026

Intranasal delivery of glioblastoma exosomes-loaded injectable chitosan hydrogel promotes neurovascular unit restoration in ischemic stroke.

Findings confirm the effective pro-angiogenic and reparative roles of A-Exos in a non-tumor ischemic microenvironment and demonstrate that intranasal H-A-Exos represents a promising therapeutic strategy for restoring NVU homeostasis and enhancing revascularization following ischemic stroke, underscoring their innovativ...

Lifei Huang, Zhihan Liu, Quanrui Zhang et al. · International Journal of Bio... · 0 citations