Wen Si

Single-cell transcriptomics reveal tissue-specific neutrophil heterogeneity and functional reprogramming in autoimmunity.

Neutrophils are increasingly recognized as key regulators of autoimmune responses; however, the mechanisms by which their heterogeneity is influenced across various tissues in autoimmunity remain insufficiently understood. Here, using experimental autoimmune encephalomyelitis (EAE), we show that splenic and bone marrow...