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Abstract Photoimmunotherapy and RNA interference (RNAi) hold great potential for tumor therapy but exhibit limited efficacy as monotherapies. In this work, we report a red‐light‐activated combinatorial therapy that integrates photodynamic immunotherapy (PIT) with RNAi via a rationally designed photosensitizer, FNBS, de...
Idiopathic pulmonary fibrosis (IPF) is a progressive refractory lung disorder with limited effective therapies. Although RNA interference (RNAi) holds promise for IPF treatment, current delivery systems are hampered by complex preparation, redundant components, and an inability to modulate oxidative stress, which sever...
Colorectal cancer (CRC) is a highly prevalent malignancy worldwide. Early diagnosis remains challenging, and its strong propensity for metastasis is a major contributor to poor patient prognosis. Current approaches for surgical guidance and photodynamic therapy (PDT) in CRC are hindered by key limitations. Imaging tech...
A triple‐stage precision nanogel platform in which carbon dots serve as organelle‑targeted delivery vehicles that achieved over 85% tumor growth inhibition with minimal systemic toxicity and offers a promising strategy to overcome key barriers in cancer therapy.
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