Author

Wen Tan

2 papers indexed here

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Open access Aug 2026

IFI44L modulates chemoradiotherapy sensitivity and CD8+ T cell infiltration in colorectal cancer

Objective Chemoradiotherapy (CRT) represents a cornerstone treatment for colorectal cancer (CRC), yet heterogeneous responses to CRT in treatment response remain a major clinical challenge. Increasing evidence suggests that the tumor immune microenvironment (TME) especially intratumoral CD8+ T cells plays an important...

Linlin Zheng, Meng-Jie Li, Ruoqing Yan et al. · Frontiers in Oncology · 0 citations

Open access Aug 2026

HDGF induces inflammatory cancer-associated fibroblast formation through ENO1-mediated glycolytic reprogramming in esophageal squamous-cell carcinoma.

An HDGF/ENO1/H4K12la/iCAF axis that links tumor metabolic reprogramming, stromal inflammatory activation, and immunosuppression in ESCC is revealed, identifying this axis as a promising therapeutic target for overcoming immunotherapy resistance.

Zhengqing Song, Cai-Nan Li, Pujie Wu et al. · Cancer Letters · 0 citations