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Review Open access Sep 2026

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

Nanotechnology has demonstrated transformative potential across molecular diagnostics, targeted drug delivery, and vaccine development; yet the majority of nanoparticle systems that show promise in preclinical settings fail to achieve clinical approval, a translational attrition rate that reflects systematic design g...

A. Ghonaim, Marwa Ahmed El-Naka, W. Nageeb et al. · 0 citations
Open access Aug 2026

Monoclonal antibodies target conserved S1B epitopes across deltacoronaviruses to inhibit porcine deltacoronavirus infection

ABSTRACT Porcine deltacoronavirus (PDCoV) is an emerging enteric pathogen that causes severe diarrhea, vomiting, and dehydration in piglets, and a recent human infection report raises concerns about its zoonotic potential. The S1 subunit of the PDCoV-spike protein is the primary target of neutralizing antibodies and is...

Jia-Ru Zhou, Ran Jing, Meng-Di Zhang et al. · 0 citations

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